Zevalin Administration Equipment

•       10 mL syringe for 0.9% NS

•       Low protein binding 0.22 micron filter

•       Syringe shield

Zevalin Administration

•        Establish venous access with butterfly needle or angiocath attached to IV tubing and 250 mL of 0.9% normal saline bag

•        Flush venous line with10 mL of 0.9% NaCl to reconfirm patency

•        Stop flow from IV bag

•       Pre wet 0.22 micron filter with NaCl 0.9%

•       Place a 0.22 micron (low protein binding) filter between the stopcock and injection port   

•       Slowly inject Y-90 or In-111 Zevalin over ten minutes

•       Slowly flush line with at least 10 mL of 0.9% NaCl after injection is completed

•       DO NOT Bolus