After studying this tutorial and taking the test, one should be able to describe the two different types of equilibrium and explain the relationship between radionuclide generators and equilibrium; should be able to give examples of each type of generator and explain the principles of separation of daughter from parent; should be able to define the term “generator” and to list the properties of the ideal generator system; should be able to identify the parts of the Mo-99/Tc-99m generator and explain the elution process; and should be able to identify the two clinically useful generators sold in the US;


1.  Definition of Parent-Daughter Equilibrium

          a. Secular Equilibrium

          b. Transient Equilibrium

2. Definition of a Generator

3. Properties of the Ideal Generator System

4. Design of a Mo/Tc Generator Column

5. Principles of Operation of a Radionuclide Generator

6. Clinically Useful Radionuclide Generators

7.  Genealogy of Mo-99

8.  Miscellaneous Information